Rotational Atherectomy in Calcified Long Lesions Demonstrated High Freedom from TLR Rate
The Importance of Real-World Data
Interventionalists have long said that many studies don’t include the types of patient and lesion characteristics that they see in real-world contemporary practice. A recent atherectomy registry observed long, 16.4 cm femoropopliteal lesions, nearly 48% of which included grade 3 or 4 calcium.
“It's a real-world registry… we didn't exclude a lot of things…” – Dr. Nicolas Shammas
The JET Registry1
Patient and Lesion Characteristics
JET Registry patients had real-world, long, femoropopliteal lesions and slightly over one-third were occluded. Calcium was visible in 90% of the lesions and grade 3 and 4 calcium was present in 47.7% of lesions.

Lesion Calcium Grades
19.5% | 4 is dense circumferential calcification along the segment length |
28.2% | 3 is aggregate calcification representing >50% of the segment length |
24.1% | 2 is aggregate calcification representing <50% of the segment length |
16.2% | 1 is one individual segment of vessel calcification representing <25% of the length of the entire segment |
10.0% | 0 is no visible calcification |
EFFICACY AND OUTCOMES
At 12 months, results showed:

Patient Safety
JET Registry results demonstrated a strong safety profile.

Procedure Details
Catheter Sizes
• 47.2% used 2.1/3.0 mm
• 49.4% used 2.4/3.4 mm
Number of Passes (average*)
• 2.0 blades down
• 1.8 blades up
Embolic Protection
• 22.4% of cases
Jetstream Runtime (average*)
• 4.7 minutes
SUBGROUP RESULTS
At 12 months, results showed:

Number of Patients: Non-Stent (157), Stent (84), Diabetic (99). Patency based on a DUS PSVR ≤2.5; Binary Restenosis Reported: Non-Stent: 20.5%; Stent: 27.8%; Diabetic Patients: 33.3%. The study was not powered to show differences between groups.
SUMMARY
JET Registry data demonstrated:
- The JET Registry saw a 77.2% patency†† rate in patients with real-world, long femoropopliteal lesions (16.4 cm). No DCBs were used in this study
- There was a high freedom from TLR rate of 81.7% at 12 months
- There was a low distal embolization rate, 1.4% or 3 events
- Calcium was present in most of the lesions and grade 3 and 4 calcium was present in 47.7% of lesions
- The Jetstream Atherectomy System had a high procedural success rate, 98.3% of patients had ≤30% residual diameter stenosis post-procedure
†† Patency based on a DUS PSVR ≤2.5; Binary Restenosis was reported as 22.8%.